PO-03-024 BENEFICIAL EFFECTS OF HIGH OUTPUT HIS BUNDLE PACING IN PATIENTS WITH HEART FAILURE AND NARROW QRS
نویسندگان
چکیده
Cardiac Resynchronization Therapy (CRT) decreases heart failure (HF) hospitalizations and mortality increases left ventricular Ejection Fraction (EF) in patients with dilated cardiomyopathy, bundle branch block QRS>130msec. However, CRT is not beneficial HF narrow QRS. We performed His Bundle Pacing (HBP) high output (3.5V/1msec) or ischemic cardiomyopathy QRS to evaluate hemodynamic benefit independent of the duration AV delay shortening. 10 male (7 patients) (3 (EF<35%) (<110ms) were referred for implantation a defibrillator. implanted an ICD- HBP system, we collected clinical, echocardiographic, electrocardiographic data. obtained all successfully. Basal mean EF was 30±4% increased 42±6% (P<0.001) after median follow-up 100 days. Left end-diastolic diameter volume decreased from 63±5 60±7ml (P=0.004) 188±78 143±38ml (P=0.029), respectively. end-systolic 136±69 84±31 (P=0.009). NYHA class by one every patient only month. Baseline remained stable pacing 107±7 118±15ms. In iatrogenic right created which corrected partially pacing. PQ shorter (from 167±23 121±14 (P=0.030) so as pace ventricle. threshold 1.24V±0.50/1msec, impedance 529±116 Ohms while R-wave 3.8±1.7mV. out patients, 1 2V/1msec 6months then stable. other nine improves function class. This appears be produced higher stimulation output. exclude that very short could favorable, measuring acute changes increase without modifications. To our knowledge these are first cases There urgent need large, randomized clinical trials.Tabled 1DataPre-implantationPost-implantationn=10n=10pEF30±442±6≤0.001LVTDV188±78143±380.029LVTSV136±6984±310.009LVTDD63±560±70.004PQ Interval167±23121±140.030QRS107±7118±150.32Follow-up:126 ±86 days Open table new tab
منابع مشابه
Pacing in heart failure patients with narrow QRS: is there more to gain than resynchronization?
Ventricular dyssynchrony is defined as uncoordinated regional myocardial contraction and relaxation and may be either interventricular or intraventricular. Most of the clinical focus has been on left ventricular (LV) intraventricular dyssynchrony, which in principle may have 3 different origins. First, dyssynchrony may have an electric origin as in left bundle-branch block, which causes nonunif...
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Metaanalysis on effects of cardiac resynchronization therapy in heart failure patients with narrow QRS complex.
BACKGROUND To systematically review the benefits of cardiac resynchronization therapy (CRT) in heart failure patients with narrow QRS (< 120 ms) who have baseline mechanical asynchrony. METHODS We searched the MEDLINE, Cochrane Central Register of Controlled Trials, and reference lists of retrieved articles for relevant trials through October 2007. Studies were included if they were clinical ...
متن کاملLong-term effectiveness of cardiac resynchronization therapy in patients with refractory heart failure and "narrow" QRS.
OBJECTIVES The aim of the study was to evaluate the effectiveness of cardiac resynchronization therapy (CRT) in patients with refractory heart failure (HF) and incomplete left bundle branch block ("narrow" QRS), together with echocardiographic evidence of interventricular and intraventricular asynchrony. BACKGROUND Cardiac resynchronization therapy has been proven effective in patients with H...
متن کاملLeft ventricular pacing improves haemodynamic variables in patients with heart failure with a normal QRS duration.
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ژورنال
عنوان ژورنال: Heart Rhythm
سال: 2023
ISSN: ['1556-3871', '1547-5271']
DOI: https://doi.org/10.1016/j.hrthm.2023.03.1040